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TC in the Family

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  • TC in the Family

    I've read that development of TC may in some instances may be genetic.

    After I was diagnosed with non-seminoma, I found out my second cousin had previously been treated for seminoma.

    Now, this maybe coincidence, but I'd be interested to know if anyone else has had more than one case of TC in their extended family.

    Diagnosed March 2006, Stage IIB, 3cm RP mass
    10% Seminoma, 90% Non-Seminoma (Embryonal, and a tiny amount of choriocarcinoma and teratoma)
    Prechemo bHCG-2648, AFP-582
    3xBEP March-June, markers normalised
    3 months postchemo - 1.2cm residual RP mass
    RPLND September 2006 - mostly necrotic tissue plus tiny amount of well differentiated teratoma
    June 2009 - TRT commenced to help out my lefty
    May 2011 - check-up, all clear

  • #2
    Hi Davie,
    My brother had TC at the age of 24 in the year 1984. I always question the genetic end of it. I asked my son's Urologist when my son was first diagnosed if indeed he thought TC was hereditary he said, no, "just bad luck". I beg to differ.
    Mother of TC survivor.
    Son, Josh 20, diagnosed Jan. 24, 2005. Left Orchiechtomy Jan.31, 2005. 4XBPE March 7th to May 28th 2005.


    • #3
      I don't know too much but I have read that genetics in fact play a role in TC, juts like Breast Cancer, if there is a family history of a type of cancer there is always a higher probability of getting it, it does not mean that is actually hereditary but you do have a higher risk.

      Fiance with Stage 1a classical seminoma, RT for 15 days
      Left I/O 3/1/06
      Firts follow up-Clear!!!


      • #4
        Yes, my oncologist made sure I told my brother to do self checks regularly because there is a higher percentage for family members to get it...
        Diagnosed 10/03/03
        I/O 10/15/03
        RPLND 1/21/04
        Completed the Boston Marathon 4/19/05
        Completed the Boston Marathon 4/17/06
        Baby Riley born on 3/29/09

        2012 Livestrong Challenge Web page


        • #5
          No relatives my mother's side have had TC. However, my mother had breast cancer.
          But, I've never had any contact with my father or his side of the family, so I don't know anything about them.
          Right I/O 4/22/1988
          RPLND 6/20/1988
          Left I/O 9/17/2003

          Tho' much is taken, much abides; and though we are not now that strength which in old days moved earth and heaven; that which we are, we are; one equal temper of heroic hearts, made weak by time and fate, but strong in will; to strive, to seek, to find, and not to yield.


          • #6

            My finace was just diagnosed at 28, and his grandfather had it at 50...he is now 72 and doing just fine.


            • #7
              There are genetic links with cancer...TC included. My paternal grandfather died from pancreatic cancer, and my paternal grandmother is surviving through colon cancer. There are no other cases of TC in my family. However, as Kev said, my brothers have to pay close attention, as do their sons...and any of my future sons too. No one knows the true cause of TC, but genetics and environmental issues are likely to play a big part and increase the odds.

              jenpat - your fiance will be fine too - just like his grandfather!

              Left I/O 5/7/05, Stage 1(pT1)
              No VI or LI, Normal Markers
              70% Embryonal, 30% Seminoma
              1st child born on 8/08


              • #8
                My husband at 35 in 1980; my son at 29 in 2004. Definitely a link.
                Spouse: I/O 8/80; embryonal, seminoma, teratoma; RPLND 9/80 - no reoccurrence - HRT 8/80; bladder cancer 11/97; reoccurrence: 4X
                Son: I/O 11/04; embryonal, teratoma; VI; 3XBEP; relapse 5/08; RPLND 6/18/08 - path: mature teratoma