Marijuana Edibles & more TC risk

[hektor2]

Just finished my year 4 surveillance after 3xBEP after non seminoma germ cell in right t that was removed. Scans and tumor markers all blood work all look good. Under an extreme amount of stress and anxiety due to pretty much everything else in my life. In my 40s. Not healthy. Other health problems (cancer risky immunosuppressing meds and other risk factors). 10-15 lbs overweight. I hadn't been able to sleep more than an 1 or 2 hrs a night for the better part of last few weeks. So after my surveillance was done, I tried some Marijuana chocolates to help sleep for 4 days. I think I had roughly 60 mg of Marijuana/THC? all together over the course of 4 days. Then I googled tc risk and marijuana and stopped. The whole chocolate bar was 300 mg, I think. I'm not sure how that stuff works. There are multiple studies if you Google, especially a bunch of recent analyses. So basically I got through 4 years of surveillance and now I am terrified after reading that marijuana can cause the specific cancer I had, testicular non seminoma germ cell etc. The first two nights I barely felt anything but the last two I was able to sleep through the night and felt that high feeling. I hadn't used since trying it as a teen and never really felt high when I did. I wish I would've just taken some Benadryl in hindsight. How bad do you guys think I screwed up? Do you think it's possible I triggered new TC in my remaining testicle with 4 days in a row of relatively high dose edibles? Should I try and get new markers done in a couple of months just to be safe?
Here are some links to what I found:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812006/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642772/

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2755855

https://archpublichealth.biomedcentral.com/articles/10.1186/s13690-022-00811-8

(Parts 2 and 3 are available online if you search for it, conclusions are all pretty scary)

[Mike]

I would not be concerned at all with your short-term use of cannabis affecting your testicular cancer or causing a relapse or new primary.

Yes, there are some studies showing an increase risk (specifically of nonseminoma, which is interesting) in those that have used cannabis but it was also more related to early age of use and length of use. None of the studies, to my knowledge, differentiated the vehicle for use (i.e. smoking flower vs. vape vs. oral ingestion).

I think what the current literature shows is that there is a possibility of cannabis causing an increased risk of nonseminoma and that for those that use it should reinforce the need for monthly self-exams.

For your situation, I would have zero concerns but would go about seeing how I can have my insomnia addressed because that is certainly going to affect quality of life long-term if you are not sleeping.

Mike

[Davepet]

Sorry I'm late to this discussion, but I agree with Mike 100%. 4 days is not enough exposure to cause a problem, I doubt even 4 months would be. There'd be a whole lot more of us here if it did.