Is there a difference in meaning between these two terms when reading clinical studies? For instance on TCRC when Dr. Craig Nic. talks about patients with clinical non-sem. stage II that have the rplnd and two courses of BEP virtually never have a recurrence. He he not talking about late relapses?
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I think both terms are interchangeable."Life moves pretty fast; if you don't stop and look around once in a while, you could miss it." -Ferris Bueller
11.22.06 -Dx the day before Thanksgiving
12.09.06 -Rt I/O; 100% seminoma, multifocal; Stage I-A; Surveillance; Six years out! I consider myself cured.
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Ditto. Relapse and recurrence are synonyms.Scott
right inguinal orchiectomy 6/5/2003 > nonseminoma, stage I > surveillance > L-RPLND 6/24/2005 for recurrence, suspected teratoma but found seminoma, stage II > chylous ascites until 9/2005 > surveillance and "all clear" since
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thanks guys.
I've just been doing research on late replases. It seem to happen roughly 2 percent of the time however it seems that most of these articles note that stage II patients that have had a successful rplnd + 2 cycles of bep seem to never relapse.
I hope they are rightMay 2000 I/O 100% Emb. Carc./June 2000 RPLND, 1 Node with Micro Involvement/ July 2000 1xBEP, 1xEP
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NonSeminoma [NS] has a greater rate of relapse than seminoma within first 2 years. But, late relapses has been oberved especialy in seminoma and unresected teratoma cases [even after 15 years]. RPLND avoid any late abdominal lymph node relapse. Therefore, I agree that in stage II NS, 2xBEP + RPLND has a very,very low rate of late relapse [but not 0 !]. RPLND eliminates the posible abdominal recurrence sites and 2xBEP cleanup the whole system from any vascular invasion.
I hate RPLND ![I never had and I hope never will]
2005-03
Stage III EC 85% + Sem 15%
AFP=2.6; HCG=10, 20,28 and rising
FULL CAT scan:
-abdominal lymph clear
-subpleural lungs metastasis [bipulmonary lesions with diam <= 1cm]
4 x BEP changed to 3 x BEP at my request
from 2005-05....Surveillance
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I hope you never have to go through the rplnd also. I did the hockey stick incision where they take out a rib. This has created a lot back and rib pain till this day. Some guys seem to recover better than others though.May 2000 I/O 100% Emb. Carc./June 2000 RPLND, 1 Node with Micro Involvement/ July 2000 1xBEP, 1xEP
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A cancer remission is a disappearance of its symptoms and its signs. It can either be partial or complete. Cure, in its strictest of definitions, would mean that it's completely gone and the chances of a recurrence are zero (or near zero)."Life moves pretty fast; if you don't stop and look around once in a while, you could miss it." -Ferris Bueller
11.22.06 -Dx the day before Thanksgiving
12.09.06 -Rt I/O; 100% seminoma, multifocal; Stage I-A; Surveillance; Six years out! I consider myself cured.
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I believe that for non-seminoma patients you are in remission when you have no signs of cancer an you are considered cured when you pass two years of remission.Son Jason diagnosed 4/30/04, stage III. Right I/O 4/30/04. Graduated College 5/13/04. 4XEP 6/7/04 - 8/13/04. Full open RPLND 10/13/04. All Clear since.
Treated by Dr. Rakowski of Midland Park, NJ. Visited Sloan Kettering for protocol advice. RPLND done at Sloan Kettering.
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Dr. Einhorn told us Jon was in remission from the day his HCG normalized and after two years it is considered cured.
Jon also had a lot of teratoma and the time frame for cure is 5 years instead of 2.Lori and Jon
Diagnosed 5/22/2006
I/O 5/26/2006, Stage 3, Good
Teratoma (Majority), Seminoma (10%), Yolk Sac
3xEP then determined not working
HDC w/stem cell transplant 8/16/06 to 9/25/06
Chest and Neck surgery 10/9/06 - immature teratoma
RPLND 11/16/06 - immature Teratoma
2/29/2008 - markers continue to be normal!
9/16/2008 - released from Dr. Einhorn's care
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