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buddy going to sloan on the 24th again.hcg increased from 26,000 to 26,200 and now to 36,000 despite gemzar and oxaliplatin.hes going to florida today.he is now taking oral etoposide.on the 24th i suspect he may be told to give bms-74550 a try,but theres NO info on it except for little on sloan ketterings own website.anyone have any info on it?thanks in advance.
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Derek12,
Sloan has a Phase II Study of BMS-247550 in Advanced Germ Cell Tumor Patients
[Protocol 03-041]
Try to google or pubmed search on BMS-247550 and you'll find tons...you had the incorrect number....Good luck to your buddy!
Retired moderator. Husband, left I/O 16Dec2005, stage I seminoma with elevated b-HCG, no LVI, RTx15 (25Gy). All clear ever since.
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Sorry to throw a url your way and run! Poked around the searches I did and BMS-247550 is in phase II trials at a few cancer centers now. It was tried in advanced colorectal cancer with no success and has been studied in a number of hormone refractory prostate cancer trials. Trials underway on breast and renal cancers as well. Looks like the phase II for tc havn't published yet from what I see. Motzer (the investigator for this trial at Sloan) should (and willas part of the patient consent) outline any toxicities that were seen in the Phase I study (on normal, helathy males).Retired moderator. Husband, left I/O 16Dec2005, stage I seminoma with elevated b-HCG, no LVI, RTx15 (25Gy). All clear ever since.Comment
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probably why i couldnt find anything.thanks alot,i found some things on a dog pile search.Comment
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