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  • #16
    Hi Al.

    I just tried to compare your values to my own, it didn't really make sense... different units, I guess. But I will say though, that allthough you may be somewhay anemic, bleomycin should be administered. I agree with Davie, that bleomycin dosen't affect yout bloodcells much, so it should just be poured in, as also suggested by Scott.

    Getting your BEP is of greater importance than having a "somewhat functioning" immune system. And red blood cells can easily be supplied by transfusions.

    How are you feeling? And do you have someone there to help you through all this?

    Best wishes
    Jens
    Embryonal carcinoma, stage II,
    3 x BEP, apr - june 2005
    Surveillance

    Comment


    • #17
      Getting your BEP is of greater importance than having a "somewhat functioning" immune system.
      Yeah I agree, I'll talk to my doctor about this tomorrow.

      I don't have anybody to help me with this but I guess it's something I have to do on my own. I take notes of what you guys say so I don't sound completely lost and become a lab rat or something like that, lots of information here.

      Thanks,

      Al
      Right IO, March 2006
      Stage III Nonseminoma - Choriocarcinoma. Multiple lung mets.

      Comment


      • #18
        25/04/2006 - 23:42

        WBC: 3.6
        RBC: 4.8
        Hb: 13.4
        PCV: 39.6
        MCV: 82
        MCH: 28
        MCHC: 33
        Platelets: 620
        Neutrophilis: 25
        Lymphocyes: 60
        Monocytes: 15

        They said that, according to this CBC test I can have the bleomycin today, finally.

        -Al
        Right IO, March 2006
        Stage III Nonseminoma - Choriocarcinoma. Multiple lung mets.

        Comment


        • #19
          That's great Al.

          A couple of paracetamols will prevent fever-like symptoms.
          And a good long nap is always a good idea while on BEP.

          Best wishes
          Jens
          Embryonal carcinoma, stage II,
          3 x BEP, apr - june 2005
          Surveillance

          Comment


          • #20
            Hi again,

            Paracetamols really do help a lot in my case, even when my chest burns I just take a couple of them and 15 minutes later I'm cured. hehe

            Had blood tests yesterday, AFP was at 1.3 and bHCG 639. I can't really understand what that means at this point (I am just starting 2nd BEP cycle) but I just thought I'd update.

            Best wishes to everyone,

            Al.
            Right IO, March 2006
            Stage III Nonseminoma - Choriocarcinoma. Multiple lung mets.

            Comment


            • #21
              Al,

              You seem to be responding superbly to chemotherapy. If you're just starting your second cycle, in 21 days you gone from a AFP of 23 to 1.3 and a bHCG of 111280 to 639.

              I understand that in the first week markers can surge, so I believe they effectively eliminate this week, and begin counting the number of half lives from the beginning of the second week of the first cycle.

              For chemotherapy your AFP concentration should halve every 5-7 days, and your bHCG concentration should halve every 2-3.5 days. Your AFP is halving every 5 days which is spot on, and your HCG is halving about every 2 days (if you rule out the first week when markers can surge) which is superb.

              The chemo is doing it's job!!

              Davie
              Diagnosed March 2006, Stage IIB, 3cm RP mass
              10% Seminoma, 90% Non-Seminoma (Embryonal, and a tiny amount of choriocarcinoma and teratoma)
              Prechemo bHCG-2648, AFP-582
              3xBEP March-June, markers normalised
              3 months postchemo - 1.2cm residual RP mass
              RPLND September 2006 - mostly necrotic tissue plus tiny amount of well differentiated teratoma
              June 2009 - TRT commenced to help out my lefty
              May 2011 - check-up, all clear

              Comment


              • #22
                keep positive....sounds like things are going your way!!!! my thoughts and prayers are with you! brian
                diagnosed 01/15/2005 bi-lateral seminoma stage IIa,4cm lymph node, right I/O & partial left I/O mar/2005, 18 days of radiation, remaining left I/O- aug/2005, surveillance, Wife did IVF oct/2005, DAD OF BABY GIRL born 08-02-2006!!! testosterone implants May 2008

                Comment


                • #23
                  Hi Al.
                  You are doing just fine. Keep those numbers comming down!

                  Chemo is good, Chemo works!!!

                  Best wishes
                  Jens
                  Embryonal carcinoma, stage II,
                  3 x BEP, apr - june 2005
                  Surveillance

                  Comment


                  • #24
                    Hi again,

                    Thanks for the info and everything guys. I just came back from chemo and got my pathology report and some other info, I will post them.

                    -----

                    Surgical Pathology Report:

                    Clinical History:
                    Right Testicular Mass.

                    Tissue origin:
                    Right testis.

                    Gross Description:

                    Received labeled with patient's name and fixed in formalin is a testis 10.5x8 5.7x3cm with an attached spermatic cord 11cm in lenght. Sectioning shows a tumour 9x7.5x7 with hemorrhagic and necrotic cut surface that appears to replace the testicular parenchyma. The tumour does not invade the tunica vaginalis or the spermatic cord.

                    Diagnosis:
                    Right testis, orchiectomy: Choriocarcinoma, biphasic (See note).

                    Note:

                    The tumour is limited to the testis and epididymis with vascular invasion and Invasion into tunica albugenia (or something), however no invasion into tunica vaginalis or into spermatic cord is noted.
                    Tumour cells are positive for HCG and Cytokeratin. They are negative for AFP, CD30 and PLAP.

                    -------------------

                    This is just what I found in a paper with stuff about my chemotherapy..

                    Bleomycin: 30mg
                    cisPlatin: 34mg
                    VP16: 170mg

                    LDH = 371 (is that too elevated?)
                    allergies: NKDA
                    --

                    That's all!

                    -Al
                    Right IO, March 2006
                    Stage III Nonseminoma - Choriocarcinoma. Multiple lung mets.

                    Comment


                    • #25
                      Originally posted by Alucard
                      ...a tumour 9x7.5x7...
                      That's a good size tumor. Couldn't have been too comfortable.
                      Scott
                      right inguinal orchiectomy 6/5/2003 > nonseminoma, stage I > surveillance > L-RPLND 6/24/2005 for recurrence, suspected teratoma but found seminoma, stage II > chylous ascites until 9/2005 > surveillance and "all clear" since

                      Your donation funds Livestrong services for people facing cancer now. Please sponsor my ride!

                      Comment


                      • #26
                        Originally posted by Scott
                        That's a good size tumor. Couldn't have been too comfortable.
                        Heh, it wasn't really a huge "ball", hehe, it was shaped like an evil potato or something.. hard to explain. The reason is that I was in the hands of a couple of retards who wanted to cure me with the most stupid tools ever and that delayed my treatment since I was diagnosed so it was growing in a weekly basis, very fast, horrible thing.. I'm glad it's gone now.

                        Scott, the report says "Choriocarcinoma, biphasic" and I didn't find much about this here in the forums.. any idea what that is? I thought I had non-seminoma..

                        -Al
                        Right IO, March 2006
                        Stage III Nonseminoma - Choriocarcinoma. Multiple lung mets.

                        Comment


                        • #27
                          Originally posted by Alucard
                          Scott, the report says "Choriocarcinoma, biphasic" and I didn't find much about this here in the forums.. any idea what that is? I thought I had non-seminoma.
                          Choriocarcinoma is one type of non-seminoma, along with embryonal carcinoma, yolk sac, and teratoma. I'm afraid I don't know the significance of its classification as biphasic versus monophasic.
                          Scott
                          right inguinal orchiectomy 6/5/2003 > nonseminoma, stage I > surveillance > L-RPLND 6/24/2005 for recurrence, suspected teratoma but found seminoma, stage II > chylous ascites until 9/2005 > surveillance and "all clear" since

                          Your donation funds Livestrong services for people facing cancer now. Please sponsor my ride!

                          Comment


                          • #28
                            Chemotherapy

                            Finished second cycle yesterday and I don't feel so bad! Can't wait to start the next cycle, 25/5/2006.

                            -Al
                            Right IO, March 2006
                            Stage III Nonseminoma - Choriocarcinoma. Multiple lung mets.

                            Comment


                            • #29
                              Hi Al.

                              How are you doing?

                              Best wishes
                              Jens
                              Embryonal carcinoma, stage II,
                              3 x BEP, apr - june 2005
                              Surveillance

                              Comment


                              • #30
                                Originally posted by Jens
                                Hi Al.

                                How are you doing?

                                Best wishes
                                Jens
                                Hi,

                                I'm doing ok, thanks. I went to the hospital today for blood tests and tomorrow I'll probably get a BEP round. Not a lot of side effects, they give me Zofran and it's perfect. Just getting too worried sometimes since I had to delay studies and other stuff because of chemotherapy.. I have a problem with anxiety but I'm getting over it. Thanks for asking.

                                -Al
                                Right IO, March 2006
                                Stage III Nonseminoma - Choriocarcinoma. Multiple lung mets.

                                Comment

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