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  • Giant Cells

    I just read the pathology report on my tumor i had removed in August. 95% Embryonal, 5% Seminoma w GIANT Cells.

    Are giant cells more difficult to kill than small cells or what?
    Diagnosed August 2005
    R/O August 2005 AFP 210

    4xEP beginning December 2005
    End Feb/March 2006 AFP 4.6
    April 2006 AFP 22 and rising

    Tandem Stem Cell Transplant 7/06 - 9/06
    December 07 AFP = 3.3
    December 07 CT = Clear!

    15+ months remission

  • #2
    I searched a bit on the internet and didn't find much on giant cells. excuse my ignorance. I'm interested in what everyone knows on this.
    Age 33, Right I/O Mar '05, 90% embryonal, 10% teratocarcinoma, Surv until 4 mo CT (+), 3 x BEP Aug/Sep '05, CT 10/05 ok, CT 2/06 ok, CT 3/06 ok, CT 6/06 ok, X-Ray, Blood 8/06 ok, Sperm Count 09/06: Low but active, CT 10/06 ok, X-ray 12/06 ok, CT 02/07 ok, X-ray/blood 4/07 ok, CT 6/07 ok, X-ray/blood 09/07, CT 10/07 ok, CT 4/08 ok, CT 10/08 ok

    LAST NIGHT I DREAMT 1000 LIES
    I CAN SEE THE DAWN
    THROUGH A DIFFERENT SET OF EYES

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    • #3
      Synctiotrophoblastic Cells. Those along with Cytotrophoblasts make choriocarcinoma. However you can have just synctiotrophoblastic cells. My initial path report had 5 % sync cells.

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      • #4
        Syncytitrophoblastic giant cells can also be found in seminoma, which is how I interpreted the pathology blurb. I have not seen any publications with enough evidence to indicate any clinical significance of the presence of giant cells in seminoma.
        Retired moderator. Husband, left I/O 16Dec2005, stage I seminoma with elevated b-HCG, no LVI, RTx15 (25Gy). All clear ever since.

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