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Beta HCG mIU/L and U/L

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  • Beta HCG mIU/L and U/L

    I just need to make sure I am doing this correct. Most material on Testicular Cancer lists the diffrent Risk Classifications for nonseminoma with levels of Beta HCG in terms of U/L and anything below 5000 U/L is good risk, between 5,000 and 50,000 U/L is Intermediate Risk and anything above 50,000 U/L is considered poor risk.

    The labs that we get from the Dr list the Beta HCG is mIU/L, the definition of which is A milli-international unit is one-thousandth of an international unit.

    So, if my husband has a lab that says his Beta HCG is 5 mIU/L that is the same as 5,000 U/L, correct?

    So anything over 50 mIU/L would be poor risk?

    I just want to make sure I am seeing this correctly. And if I am, why in the world do they write it up this way?

    Becki

    Husband Right I/O 09/06
    -70% Embryonal Carcinoma
    -20% Teratoma
    -10% Yolk Sac Tumor
    11/06- lymph nodes 1.8x1.4 and 1.9x1.4
    12/06-PET Scan confirms activity in lymph nodes, lymph nodes 2.2x2.2 and 2.4x2.3
    1/07-Start 3xBEP
    4/07-PET clear, lymph nodes down to 1.1x0.5 and 1.8x1.0
    6/07-lymph nodes 1.2x1.0 and 1.9x.9
    8/07-lymph nodes 1.1x1.0 and 2.0x1.2
    10/07-lymph nodes 2.0x1.5 and 2.7x1.8
    11/07- PostChemo LRPLND-found burnt out teratoma
    11/09-Enlarging lymph node 1.2 cm near renal veins

  • #2
    yes...

    here is an article with the standards...



    so when my bhcg came in at 4.6...it was 4600mu/l
    - lump first noticed 11/20/2005
    - I/O right Dec 8, 2005
    - 95% embryonal / 5% seminoma
    - normal markers PRE surgery
    - no vascular invasion, tunica free of cancer, epididymis free of cancer, lungs free, lymph free
    - Stage I diagnosis
    - surveillance
    - mid feb '06, beta hcg slightly elevated = 4.6...small enlarged lower node seen on CT scan...
    - 3BEP began feb 20, 2006
    - finished 3 BEP, last bleo, april 17, 2006
    - CT scan, blood markers, chest..all clear
    - back on surveillance

    Comment


    • #3
      Good risk: hCG <5,000 mIU/mL
      Intermediate risk: hCG 5,000-50,000 mIU/mL
      Poor risk: hCG >50,000 mIU/mL

      1 mIU/mL = 1 IU/L = 1,000 mIU/L

      So, if my husband has a lab that says his Beta HCG is 5 mIU/L that is the same as 5,000 U/L, correct?
      5 mIU/L = 0.005 IU/L
      5,000 IU/L = 5,000 mIU/mL = 5,000,000 mIU/L
      So anything over 50 mIU/L would be poor risk?
      Anything over 50,000 mIU/mL is poor risk. 50 mIU/L = 0.05 mIU/mL.
      Scott
      right inguinal orchiectomy 6/5/2003 > nonseminoma, stage I > surveillance > L-RPLND 6/24/2005 for recurrence, suspected teratoma but found seminoma, stage II > chylous ascites until 9/2005 > surveillance and "all clear" since

      Your donation funds Livestrong services for people facing cancer now. Please sponsor my ride!

      Comment


      • #4
        My mistake

        I am sorry, I should have put my husbands Beta HCG was 5 mIU/mL not 5 mIu/L

        But thank you for all the math Scott

        And I have now seen it listed as

        Good risk: hCG <5,000 mIU/mL (this web site)

        and

        Good risk: HCG <5,000 U/L (on the web site Pete reffered to and the National Comprehensive Cancer Network)

        So I am honestly compleatly confused on what is what.

        But if you check, you will see they are listed differently. And if I am not compleatly loosing my math sense, they are not the same thing, right?

        I am sorry to be so confused.

        Becki

        Husband Right I/O 09/06
        -70% Embryonal Carcinoma
        -20% Teratoma
        -10% Yolk Sac Tumor
        11/06- lymph nodes 1.8x1.4 and 1.9x1.4
        12/06-PET Scan confirms activity in lymph nodes, lymph nodes 2.2x2.2 and 2.4x2.3
        1/07-Start 3xBEP
        4/07-PET clear, lymph nodes down to 1.1x0.5 and 1.8x1.0
        6/07-lymph nodes 1.2x1.0 and 1.9x.9
        8/07-lymph nodes 1.1x1.0 and 2.0x1.2
        10/07-lymph nodes 2.0x1.5 and 2.7x1.8
        11/07- PostChemo LRPLND-found burnt out teratoma
        11/09-Enlarging lymph node 1.2 cm near renal veins

        Comment


        • #5
          "U" just means "unit," and "IU" means "international unit," and they're the same thing here. The m's cancel each other out, so 1 mIU/mL = 1 IU/L.
          Scott
          right inguinal orchiectomy 6/5/2003 > nonseminoma, stage I > surveillance > L-RPLND 6/24/2005 for recurrence, suspected teratoma but found seminoma, stage II > chylous ascites until 9/2005 > surveillance and "all clear" since

          Your donation funds Livestrong services for people facing cancer now. Please sponsor my ride!

          Comment


          • #6
            I understand that U is for unit, what I am not quite catching is why 1 mIU/mL = 1 IU/L?

            To my brain that is the same as saying 1 mL = 1L (one mililiter equals one liter)

            Maybe I am just missing something...

            Clearly my brain is not awake and I need to look at it some...

            sorry about that!

            Husband Right I/O 09/06
            -70% Embryonal Carcinoma
            -20% Teratoma
            -10% Yolk Sac Tumor
            11/06- lymph nodes 1.8x1.4 and 1.9x1.4
            12/06-PET Scan confirms activity in lymph nodes, lymph nodes 2.2x2.2 and 2.4x2.3
            1/07-Start 3xBEP
            4/07-PET clear, lymph nodes down to 1.1x0.5 and 1.8x1.0
            6/07-lymph nodes 1.2x1.0 and 1.9x.9
            8/07-lymph nodes 1.1x1.0 and 2.0x1.2
            10/07-lymph nodes 2.0x1.5 and 2.7x1.8
            11/07- PostChemo LRPLND-found burnt out teratoma
            11/09-Enlarging lymph node 1.2 cm near renal veins

            Comment


            • #7
              Does it help to see it this way?

              1 mIU
              -------
              1 mL

              =

              1 IU
              -----
              1 L
              Scott
              right inguinal orchiectomy 6/5/2003 > nonseminoma, stage I > surveillance > L-RPLND 6/24/2005 for recurrence, suspected teratoma but found seminoma, stage II > chylous ascites until 9/2005 > surveillance and "all clear" since

              Your donation funds Livestrong services for people facing cancer now. Please sponsor my ride!

              Comment


              • #8
                1 meter = 1000 millimeters
                1 liter = 1000 milliliters

                1 mIU/mL = 1 IU/L?

                The "1" in the equation above is just a ratio. For instance:

                50 cars/street = 5000 cars/100 streets

                The ratio 50/1 = 5000/100

                So they would simplify the ratio to just 50/1 on both side

                Comment


                • #9
                  I am going to just pretend I understand. I am sure I most likely understand.

                  I think more then anything I am just super paranoid right now that they are missing something. The oncologist keeps forgetting to do things and now we are fighting with the insurance company to move forward with any diagnostics or treatment, and honestly it is driving me crazy.

                  And I can't get my husband to agree to seek another opinion at all. He trusts the oncologist and everyone else 100%, without question.

                  And I can't seem to shake that feeling that something is being missed. I've always trusted my God given women's intuition before and it is really hard to ignore it right now.

                  I'll keep on pushing!

                  Becki

                  Husband Right I/O 09/06
                  -70% Embryonal Carcinoma
                  -20% Teratoma
                  -10% Yolk Sac Tumor
                  11/06- lymph nodes 1.8x1.4 and 1.9x1.4
                  12/06-PET Scan confirms activity in lymph nodes, lymph nodes 2.2x2.2 and 2.4x2.3
                  1/07-Start 3xBEP
                  4/07-PET clear, lymph nodes down to 1.1x0.5 and 1.8x1.0
                  6/07-lymph nodes 1.2x1.0 and 1.9x.9
                  8/07-lymph nodes 1.1x1.0 and 2.0x1.2
                  10/07-lymph nodes 2.0x1.5 and 2.7x1.8
                  11/07- PostChemo LRPLND-found burnt out teratoma
                  11/09-Enlarging lymph node 1.2 cm near renal veins

                  Comment

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