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Fertility and HDC

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  • Fertility and HDC

    Anyone have an idea of the likelihood to be sterile after HDC w/stem cell (etoposide + carboplatin). Is there a chance it would come back within a few years??!
    Diagnosed August 2005
    R/O August 2005 AFP 210

    4xEP beginning December 2005
    End Feb/March 2006 AFP 4.6
    April 2006 AFP 22 and rising

    Tandem Stem Cell Transplant 7/06 - 9/06
    December 07 AFP = 3.3
    December 07 CT = Clear!

    15+ months remission

  • #2
    .

    For standard BEP(EP) regimen the probability is 70-80 %
    HDC alone reduces it to 30-40 %
    BEP(EP) + HDC 10-20 % [even worse]
    2005-03
    Stage III EC 85% + Sem 15%
    AFP=2.6; HCG=10, 20,28 and rising
    FULL CAT scan:
    -abdominal lymph clear
    -subpleural lungs metastasis [bipulmonary lesions with diam <= 1cm]
    4 x BEP changed to 3 x BEP at my request
    from 2005-05....Surveillance

    Comment


    • #3
      Ok thanks Adrian. .just kinda wondering about the future!
      Diagnosed August 2005
      R/O August 2005 AFP 210

      4xEP beginning December 2005
      End Feb/March 2006 AFP 4.6
      April 2006 AFP 22 and rising

      Tandem Stem Cell Transplant 7/06 - 9/06
      December 07 AFP = 3.3
      December 07 CT = Clear!

      15+ months remission

      Comment

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