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Time for a decision

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  • #16
    Originally posted by tccancercop
    Are you sure of this or is it that Seminoma doesn't always show in bloodwork??? I had 95% Embryonal so how do you know if it doesn't always show up in blood work (AFP)??????????????????????????????
    The TCRC says hCG is elevated in 80% of, and AFP is elevated in 75% of, embryonal carcinoma cases. Markers do show up often, but this is why x-rays, CT scans, and physical examination are all important, too.
    right inguinal orchiectomy 6/5/2003 > nonseminoma, stage I > surveillance > L-RPLND 6/24/2005 for recurrence, suspected teratoma but found seminoma, stage II > chylous ascites until 9/2005 > surveillance and "all clear" since

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    • #17
      I'm not a math geek but I believe that would give us about 5% that would have no elevation in markers. That's certainly higher then I would have thought.
      Son Jason diagnosed 4/30/04, stage III. Right I/O 4/30/04. Graduated College 5/13/04. 4XEP 6/7/04 - 8/13/04. Full open RPLND 10/13/04. All Clear since.

      Treated by Dr. Rakowski of Midland Park, NJ. Visited Sloan Kettering for protocol advice. RPLND done at Sloan Kettering.


      • #18
        Based only by the math, the likelihood of showing markers in a tumor whose composition is 5% EC and 95% seminoma is about 7% (for HCG and AFP combined).
        Just to clarify, since the last three of posts refer back to one I made earliker in the thread:
        Originally posted by Fed
        Embryonal doesn't always show markers, so it seems that in your case, the bloodwork won't help much in the decision making.
        My line of thinking was that with such an overwhelming composition of seminoma, it would be difficult to make a conclusive call on prognosis using markers alone, hence the reason I concluded that "the bloodwork won't help much in the decision making." Like Scott said, this is why there are additional components necessary for an accurate diagnosis (CT scans, X-rays) and subsequent treatment decisions. Hopefully this clears out the confusion.
        "Life moves pretty fast; if you don't stop and look around once in a while, you could miss it." -Ferris Bueller
        11.22.06 -Dx the day before Thanksgiving
        12.09.06 -Rt I/O; 100% seminoma, multifocal; Stage I-A; Surveillance; Six years out! I consider myself cured.


        • #19

          I had 85%EC and only HCG where elevated. AFP always was uin normal range
          Stage III EC 85% + Sem 15%
          AFP=2.6; HCG=10, 20,28 and rising
          FULL CAT scan:
          -abdominal lymph clear
          -subpleural lungs metastasis [bipulmonary lesions with diam <= 1cm]
          4 x BEP changed to 3 x BEP at my request
          from 2005-05....Surveillance